AMT Succinate
What is AMT?
α-Methyltryptamine (also known as Indopan and commonly as αMT or aMT) is a lesser-known entactogen substance of the tryptamine class.[1]
αMT was originally developed by Upjohn in the 1960s.[2] It was briefly used in the Soviet Union as an antidepressant under the trade name Indopan.[1][3][4][5] Indopan was prescribed in 5-10 mg doses, which is significantly lower than the dose used for recreational effects.
Erowid has received “a handful of unverifiable reports of hospitalization after high-dose (over 60 mg oral) αMT ingestion.”[6] There were 22 deaths linked to αMT in England and Wales where the drug became popular as a legal high from 2012 until it was banned in early 2015.[7]
Limited data exists about the pharmacological properties, metabolism, and toxicity of aMT, and it has a limited history of non-medical human use. It is highly advised to use harm reduction practices if using this substance.
Chemical Properties
αMT, or α-Methyltryptamine is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. AMT is substituted at the alpha carbon Rα of its tryptamine backbone with a methyl group.
AMT is found in freebase form as a racemate of its (R-) and (S-) enantiomers.
Pharmacological effects
αMT’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist.
αMT also acts as a releasing agent of serotonin, noradrenaline, and dopamine.[8][9] It also acts as a very weak, non-selective RIMA in-vitro[10] and in-vivo.[11], but this is unlikely to be very significant (if at all) with common doses.
Some of the most commonly reported effects are:
Stimulation
Anxiety suppression
Disinhibition
Empathy, affection, and sociability enhancement
Analysis enhancement
Conceptual thinking
Emotion enhancement
Cognitive euphoria
Immersion enhancement
Increased music appreciation
Memory suppression
Ego death
Thought acceleration
Thought connectivity
Time distortion
Wakefulness
Acuity enhancement
Colour enhancement
Pattern recognition enhancement
Potential Side Effects
Difficulty urinating – A slight difficulty urinating is occasionally present.
Temperature regulation suppression
Headaches
Abnormal heartbeat
Increased blood pressure
Increased heart rate
Increased perspiration
Nausea
Pupil dilation
Legality
AMT is classified as illegal in:
Australia: AMT is illegal to possess, produce and sell. It is controlled as an analog of 5-MeO-AMT, which is a schedule 9 controlled substance.
Austria: AMT is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).
China: As of October 2015 AMT is a controlled substance in China.
Denmark: In 2010, the Danish Minister for the Interior and Health placed AMT on their lists of controlled substances (List B).
Germany: AMT is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of January 31, 1993. It is illegal to manufacture, possess, import, export, buy, sell, procure, or dispense it without a license.
Greece: AMT is illegal to possess, produce, and sell.
Hungary: AMT was controlled on the Schedule C list in Hungary in 2013.
Japan: AMT is illegal to possess, produce, and sell.
Latvia: AMT is a Schedule I drug.
Lithuania: As of 2012, AMT is controlled as a tryptamine derivative under the 1st list of Narcotic Drugs and Psychotropic Substances which prohibits its use for medical purposes.
Russia: AMT is illegal to possess, produce, and sell.
Slovakia: AMT was placed on the List of Hazardous Substances in Annex, § 2 in Slovakia in 2013.
Slovenia: AMT appeared on the Decree on Classification of Illicit Drugs in 2013.
Spain: AMT is controlled according to the Act on the Prohibition of Certain Goods.
Sweden: AMT is illegal to possess, produce, and sell.
Switzerland: AMT, along with AET are controlled substances specifically named under Verzeichnis D.
United Kingdom: AMT is a Class A drug in the United Kingdom as a result of the tryptamine catch-all clause.
This list is not exhaustive, so do your own research into the legal status in your country before ordering!