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AMT Succinate

AMT Succinate

What is AMT?

α-Methyltryptamine (also known as Indopan and commonly as αMT or aMT) is a lesser-known entactogen substance of the tryptamine class.[1]

αMT was originally developed by Upjohn in the 1960s.[2] It was briefly used in the Soviet Union as an antidepressant under the trade name Indopan.[1][3][4][5] Indopan was prescribed in 5-10 mg doses, which is significantly lower than the dose used for recreational effects.

Erowid has received “a handful of unverifiable reports of hospitalization after high-dose (over 60 mg oral) αMT ingestion.”[6] There were 22 deaths linked to αMT in England and Wales where the drug became popular as a legal high from 2012 until it was banned in early 2015.[7]

Limited data exists about the pharmacological properties, metabolism, and toxicity of aMT, and it has a limited history of non-medical human use. It is highly advised to use harm reduction practices if using this substance.

Chemical Properties

αMT, or α-Methyltryptamine is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. AMT is substituted at the alpha carbon Rα of its tryptamine backbone with a methyl group.

AMT is found in freebase form as a racemate of its (R-) and (S-) enantiomers.

Pharmacological effects

αMT’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist.

αMT also acts as a releasing agent of serotonin, noradrenaline, and dopamine.[8][9] It also acts as a very weak, non-selective RIMA in-vitro[10] and in-vivo.[11], but this is unlikely to be very significant (if at all) with common doses.

Some of the most commonly reported effects are:

Stimulation

Anxiety suppression

Disinhibition

Empathy, affection, and sociability enhancement

Analysis enhancement

Conceptual thinking

Emotion enhancement

Cognitive euphoria

Immersion enhancement

Increased music appreciation

Memory suppression

Ego death

Thought acceleration

Thought connectivity

Time distortion

Wakefulness

Acuity enhancement

Colour enhancement

Pattern recognition enhancement

Potential Side Effects

Difficulty urinating – A slight difficulty urinating is occasionally present.

Temperature regulation suppression

Headaches

Abnormal heartbeat

Increased blood pressure

Increased heart rate

Increased perspiration

Nausea

Pupil dilation

Legality

AMT is classified as illegal in:

Australia: AMT is illegal to possess, produce and sell. It is controlled as an analog of 5-MeO-AMT, which is a schedule 9 controlled substance.

Austria: AMT is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).

China: As of October 2015 AMT is a controlled substance in China.

Denmark: In 2010, the Danish Minister for the Interior and Health placed AMT on their lists of controlled substances (List B).

Germany: AMT is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of January 31, 1993. It is illegal to manufacture, possess, import, export, buy, sell, procure, or dispense it without a license.

Greece: AMT is illegal to possess, produce, and sell.

Hungary: AMT was controlled on the Schedule C list in Hungary in 2013.

Japan: AMT is illegal to possess, produce, and sell.

Latvia: AMT is a Schedule I drug.

Lithuania: As of 2012, AMT is controlled as a tryptamine derivative under the 1st list of Narcotic Drugs and Psychotropic Substances which prohibits its use for medical purposes.

Russia: AMT is illegal to possess, produce, and sell.

Slovakia: AMT was placed on the List of Hazardous Substances in Annex, § 2 in Slovakia in 2013.

Slovenia: AMT appeared on the Decree on Classification of Illicit Drugs in 2013.

Spain: AMT is controlled according to the Act on the Prohibition of Certain Goods.

Sweden: AMT is illegal to possess, produce, and sell.

Switzerland: AMT, along with AET are controlled substances specifically named under Verzeichnis D.

United Kingdom: AMT is a Class A drug in the United Kingdom as a result of the tryptamine catch-all clause.

This list is not exhaustive, so do your own research into the legal status in your country before ordering!

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